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A Potential Development Program To Help Glioblastoma

November 13, 2015 | Author: | Posted in Health and Fitness

Oncology drug development company Celsion recently spoke about its recent development in the way of helping those with brain cancer. Specifically, the company would focus on glioblastoma, which is commonly regarded in this field of research. It’s not hard to see why, as this particular tumor has been considered the most serious and aggressive form of tumor in the brain. Can a new approach by this company, though, prove to be helpful for not only patients who are afflicted but the entire scope of research seen here?

According to an article posted on Pharmaceutical Business Review, there is quite a bit of potential to talk about when concerning this approach. If successful, it will be able to help tumors in the brain, with glioblastoma being the main focus and understandably so. Voices against Brain Cancer, as well as other organizations, have given this particular condition a great deal of focus. That being said, there are a couple of details which, in my opinion, are ones that are more than worth going into detail over.

The company will bring together a number of experiments that would be able to prove the effectiveness of ThermoDox in addition to MR guided high intensity ultrasound efforts. Animal subjects will be tested on first and, if results are positive, the efforts will be transitioned to human efforts. According to the words of Dr. Nicholas Borys, Thermodox can provide a tremendous benefit, as it is a, “heat-activated liposomal encapsulation of doxorubicin.” Seeing as how this could be utilized in order to help separate types of cancer, its importance is tremendous.

A phase III HEAT study was done with ThermoDox put into effect in tandem with RFA. The study in question was done to see how well patients reacted to this combination as opposed to simply RFA on its own. When the results from the study came to the surface, it was determined that ThermoDox drastically improved PFS, not to mention overall survival rates in patients if their lesions undergo RFA for 45 minutes or so. Simply put, there are results to be seen with this approach.

I have to believe that greater results can come to the surface in due time. In my mind, the ThermoDox approach holds tremendous potential, especially when given how the approach has been utilized in the past. Liver cancer, for example, has been focused on and the same could be said about other forms of this condition as well. By this information, it appears as though there are results to be had when it comes to helping patients that have been stricken with brain cancer as well.

If you’d like further details about glioblastoma, please go to Voices against Brain Cancer.


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